Research view


Title: Callous–unemotional traits in conduct disorder in relation to salivary cortisol level
Author: Hani H. Dessoki, Heba F. Abd El Reheem, Maha E. Ahmed, Mohamed R. Soltan, Ahmed A. Abdel Hakim and Mariam E. Dawoud
Objectives To show the correlation between items of Callous Unemotional Inventory (CUI) and Conduct Disorder and to assess correlation between salivary cortisol and Conduct Disorder. Background Emerging evidence suggests that low levels of cortisol may act as a biological marker for the Callous Unemotional traits (CU Traits) subgroup of Conduct Disorder. Materials and methods The current study tested the presence of items of Callous Unemotional Inventory (CUI) and the salivary cortisol level among group of patients with Conduct Disorder (Forty patients from 12 to 16 years old, diagnosed according to criteria of DSM IV and recruited from Kasr El Aini Psychiatric hospital) and group of control (Forty healthy volunteers). Both groups were subjected to Callous Unemotional traits Inventory and salivary cortisol level was assessed using ELISA. Results Patient group showed high levels of CU traits compared to control group. Patient group showed significant difference in salivary cortisol level (mean is 3.188 ±1.1108) compared to control group (mean is 5.01±1.846).This study found correlation between Callous traits and severity of Conduct Disorder. Conclusion The current findings build upon recent research in suggesting that lowcortisol levelmay be a biological marker for patients with Conduct Disorder and high levels of CU traits. Keywords: callous–unemotional traits, conduct disorder, disruptive disorder, salivary cortisol
Distributor: Egypt J Psychiatr 38:90–96