Research view
| Title: | An Open Non Comparative Study for the Evaluation of Efficacy and Safety of “Sertraline” in the Treatment of Major Depressive Disorder |
| Author: | Okasha A. , Assad T. |
| Abstract: |
The study included 30 patients fulfilling the DSM-III-R criteria for major depression. Patients were given sertraline after washout period in case previous anti-depressants were used before. Doses were to be evaluated and increased when required every two weeks. Assessments were done on days 0,14, 28, 42 and 56 using Hamilton .Depression and Anxiety scales, CGI and other scales for side effects. The results showed satisfactory significant improvement as shown by scores of HAMD and CGI. The drug was found well tolerable with no report of significant serious side effect. |
| Journal: | Current Psychiatry, vol 1, num 2 |
| Text: | |