Research view

Title: Novel Mutation Causing Partial Biotinidase Deficiency in a Syrian Boy with Infantile Spasms and Retardation.
Author: Mikati, Mohamad A.; Zalloua, Pierre; Karam, Pascale; Habbal, Mohamad-Zuheir; Rahi, Amal C.
Abstract:
We report a case of partial biotinidase deficiency (plasma biotinidase levels: 1.30 nm/minute/mL) in a 7-month-old boy who presented with evidence of perinatal distress followed by developmental delay, hypotonia, seizures, and infantile spasms without alo
Journal: Journal of Child Neurology. 2006 Nov Vol 21(11) 978-981