Research view
| Title: | Maternal balanced translocation (4;21) leading to an offspring with partial duplication of 4q and 21q without phenotypic manifestations of Down syndrome |
| Author: | El-Ruby M, Hemly NA, Zaki MS. |
| Abstract: |
We describe an 8-years old female with supernumerary chromosome
der(21)t(4;21)(q25;q22) resulting in partial trisomy 4q25-qter and partial
trisomy 21(pter-q22). The extra material was originated from a reciprocal
balanced translocation carrier mother (
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| Journal: | Genet Couns. 2007;18(2):217-26. |