Research view
| Title: | Attenuation of morphine tolerance and dependence by aminoguanidine in mice |
| Author: | Abdel-Zaher AO, Hamdy MM, Aly SA, Abdel-Hady RH, Abdel-Rahman S. |
| Abstract: |
The effect of aminoguanidine, an inducible nitric oxide synthase (iNOS)
inhibitor, on morphine-induced tolerance and dependence in mice was investigated
in this study. Acute administration of aminoguanidine (20 mg/kg, p.o.) did not
affect the antinoci
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| Journal: | Eur J Pharmacol. 2006 Jul 1;540(1-3):60-6. Epub 2006 Apr 1 |