Research view

Title: Multiple enzyme inhibitions by histamine H3 receptor antagonists as potential procognitive agents.
Author: Petroianu G, Arafat K, Sasse BC, Stark H.
Abstract:
Novel highly affine histamine H3 receptor ligands with additional inhibitory effects on the main histamine metabolizing enzyme in the brain, N-methyltransferase, chemically show structural elements of the acetylcholinesterase inhibitor tacrine. H3 rece
Journal: Pharmazie. 2006 Mar;61(3):179-82.