Research view
| Title: | Long-term effects of acute and of chronic hypoxia on behavior and on hippocampal histology in the developing brain. |
| Author: | Mikati MA, Zeinieh MP, Kurdi RM, Harb SA, El Hokayem JA, Daderian RH, Shamseddine A, Obeid M, Bitar FF, El Sabban M. |
| Abstract: |
Ten-day-old rat pups (P10) subjected to acute hypoxia (down to 4% O2) had as
adults increased aggression (handling test), memory impairment (water maze test),
and decreased CA1 cell counts. Pups subjected to chronic hypoxia (10% O2 from P0
to P21) had
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| Journal: | Brain Res Dev Brain Res. 2005 Jun 9;157(1):98-102. Epub 2005 Apr 26. |