Research view
Title: | Assessment of cognitive functions in children on regular hemodialysis and after renal transplantation |
Author: | Fadia Zyada, Samuel H. Makar, Safaa M. Abdelrahman and Ahmed H. Labana |
Abstract: |
Background
End-stage renal disease is a complicated disorder associated with specific problems
occurring in children, such as impaired growth and psychosocial adjustment, in
addition to cognitive affection. The lifespan and outcome of end-stage renal disease
children have improved markedly since the development of dialysis techniques and
kidney transplantation. The aim of our study was to compare cognitive functions in
children on regular hemodialysis (HD) with children after successful renal
transplantation (RTx).
Patients and methods
This study was carried out at the center of Paediatric Nephrology and Transplantation,
Cairo University, where 20 children on regular HD, 20 children after successful RTx,
and 20 children as healthy controls were assessed. The Wechsler Intelligence Scale
for Children was used for the assessment of cognitive functions.
Results
Children on regular HD and those after successful RTx were found to have a significant
impairment in cognitive functions in all subtests including the full-scale intelligent
quotient, verbal intelligent quotient, and performance intelligent quotient among HD
and post-RTx patients compared with the healthy controls. Also, impaired cognitive
functions were significantly lower in the children on dialysis compared with the post-
RTx group.
Conclusion
Children on regular HD and after successful RTx have more impaired cognitive
functions than healthy controls.
Keywords:
children, cognitive functions, hemodialysis, renal transplantation
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Journal: | Middle East Curr Psychiatry 24:128–13 |
Text: | |
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